The South Carolina Highway Patrol is investigating a deadly crash on SC 125 in Barnwell County.
Investigators say it happened around 3:20 pm on Thursday.
Lance Cpl. Judd Jones says the driver of a 2008 Honda was driving north on SC 125 when they swerved into the southbound lane and hit another car.
The driver, 53-year-old Gloria Williams, was not wearing a seatbelt. She was taken to AU Medical Center where she later died.
The passenger was also taken to the hospital with serious injuries. Officials say neither were wearing a seatbelt.
The driver of the second car was also taken to the hospital for treatment.
No word yet on if any charges will be filed.