Dr. Abdullah Kutlar, Hematologist at Georgia Regents Medical Center says, "People with this MTHFR mutation had higher rates of heart attack, coronary artery disease compared to those who didn't have."
Kutlar says MTHFR is very common and in some cases it can be dangerous.
Kutlar says, "Homocysteine in higher concentrations can be toxic to your endothelin, your vessel walls."
Dr. Kutlar says you are at higher risk if you have a history of blood clots.
Kutlar says, "Increasing the chances of clotting because it causes damage to the endothelin inner wall of the blood vessels and that facilitates clot formation."
He says that although the mutation is not life-threatening for most people, it still can have negative effects.
Kutlar says, "If you have this mutation your chance of developing any blood clots, etc. is one point two fold. Which is like a 20% increase over the general population."
But if you have other genetic mutations along with MTHFR the dangers are serious. It's a rare disease, but it is deadly to some.
Kutlar says, "They have very high homocysteine levels and that causes a number of defects in vessel walls, also neurological defects and these children if not treated die at a very early age because of premature heart attacks and so forth which is related to this."
Good news is that it's a genetic mutation that can be easily fixed, but not with over-the-counter vitamins.
Kutlar says, "No, actually it has to be prescription stuff. Over the counter vitamin preparations contain only 400 micro grams of folic acid."
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